Persistence of Intra-articular Steroid

Intra-articular steroid therapy in rheumatoid arthritis.

The introduction of steroid preparations into joint cavities has become a routine method of treating some cases of rheumatoid arthritis. Murdoch and Will (1959a, b) have drawn attention to the persistence of prednisolone trimethyl acetate (P.T.M.A.) in the joint cavity and to its, apparently, purely local effect when administered in this way. Since then, Triamcinolone (T.C.A.), Dexamethasone (D...

Importance of placement of intra-articular steroid injections.

Release of lubricating synovial surfactant by intra-articular steroid.

This study was undertaken to determine whether glucocorticosteroids promote the secretion of lubricating surfactant, i.e. surface-active phospholipid (SAPL), into the joint. A standard clinical dose (100 mg) of methylprednisolone acetate (MPA) in 2.5 ml of saline was injected into the load-bearing right radiocarpal joint of five horses and 2.5 ml of saline injected into each of the contralatera...

[comparison of Intra Articular Steroid vs. Hydraulic Distention for the Treatment of Frozen Shoulder Singh

It was a prospective, observational, comparative and clinical study. Sixty patients were selected from Dhanusha District of Janakpur, Nepal. They were divided into two groups. Since January 2005 to January 2006 periods in the department of orthopedics surgery, Janaki Medical College & Teaching Hospital, Janakpur. The Group I was treated by hydraulic distention of glenohumeral joint with 50ml no...

Intra-articular steroid injection in acute rheumatoid arthritis of the larynx.

A case of stridor due to rheumatoid arthritis of the cricoarytenoid joints is presented, with special emphasis on a new line of treatment by local intra-articular steroid injection.